Top 40 Hits of May 2005
| 1 | Akon | Lonely |
| 2 | Tony Christie featuring Peter Kay | (Is This The Way To) Amarillo |
| 3 | Snoop Dogg featuring Charlie Wilson & Justin Timberlake | Signs |
| 4 | Gorillaz | Feel Good Inc |
| 5 | Bodyrockers | I Like The Way |
| 6 | Will Smith | Switch |
| 7 | Oasis | Lyla |
| 8 | Ciara featuring Missy Elliott | 1, 2 Step |
| 9 | Destiny's Child | Girl |
| 10 | Eminem | Mockingbird |
| 11 | The Game featuring 50 Cent | Hate It Or Love It |
| 12 | Razorlight | Somewhere Else |
| 13 | Crazy Frog | Axel F |
| 14 | Mario | Let Me Love You |
| 15 | The Black Eyed Peas | Don't Phunk With My Heart |
| 16 | 50 Cent | Candy Shop |
| 17 | Caesars | Jerk It Out |
| 18 | The Coral | In The Morning |
| 19 | Elvis vs JXL | A Little Less Conversation |
| 20 | Coldplay | Speed Of Sound |
| 21 | Studio B | I See Girls |
| 22 | Lil' Jon & The East Side Boyz | Get Low / Lovers And Friends |
| 23 | Faith Evans | Again |
| 24 | Kelly Osbourne | One Word |
| 25 | Weezer | Beverly Hills |
| 26 | Jennifer Lopez featuring Fat Joe | Hold You Down |
| 27 | Jem | They |
| 28 | Mariah Carey | It's Like That |
| 29 | Athlete | Half Light |
| 30 | The Killers | Smile Like You Mean It |
| 31 | The Tears | Refugees |
| 32 | Natalie Imbruglia | Shiver |
| 33 | Gwen Stefani featuring Eve | Rich Girl |
| 34 | Lemar | Time To Grow |
| 35 | Max Graham vs Yes | Owner Of A Lonely Heart |
| 36 | Rooster | You're So Right For Me |
| 37 | KT Tunstall | Other Side Of The World |
| 38 | Freeloaders featuring The Real Thing | So Much Love To Give |
| 39 | Amerie | 1 Thing |
| 40 | McFly | All About You / You've Got A Friend |